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Lung Ultrasound for Community-acquired Pneumonia Diagnosis in Emergency Medicine

Lung Ultrasound for Community-acquired Pneumonia Diagnosis in Emergency Medicine

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03411824
Acronym
ECHOPAC
Enrollment
90
Registered
2018-01-26
Start date
2016-11-08
Completion date
2019-02-08
Last updated
2021-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community Acquired Pneumonia

Keywords

diagnosis, Point-of-Care-Ultrasound, lung ultrasound

Brief summary

Community-acquired pneumonia (CAP) is frequently suspected in the Emergency Department (ED). However, usual diagnosis procedure based on clinical features and chest X-Ray has rather bad performances. A recent study on CT performance in suspected CAP found that 58% of classifications were modified by CT when compared with usual procedure. However, extended CT usage in CAP diagnosis is associated with many limitations : availability in a majority of ED, delay, cost and irradiation, in particular In young patients. Lung Ultrasound (LUS) has good performances in CAP diagnosis even when compared with CT. It is a rapid, inexpensive, radiation-free tool available in a majority of ED. It is performed at the patient's bedside with immediate results. The learning curve allows Emergency Physicians (EP) to perform this exam after a relative brief training. The Investigators aim to investigate LUS performances in clinically suspected CAP authentication , and assesses specific diagnostic contributions and impact on antibiotic prescriptions .

Detailed description

120 patients will be enrolled on CAP suspicion. All explorations (radiography…) and biological exams (blood culture…) will be performed as usual to build physician primary diagnosis. Complementarily, an EP will be realized and final diagnosis will be made by physician. Finally, at Day28 expert adjudication committee will authentic diagnosis considering explorations and clinical issues. Frequency of discordant diagnosis between 1st and 2nd assessment and against expert will be measured Primary Purpose: diagnostic Study Phase: Not Applicable Intervention Model: NA Number of Arms: 1 Masking: open label, Masked Roles: NA Allocation: NA Study Endpoint Classification: efficacy Enrollment: 120 subjects (anticipated )

Interventions

OTHERno intervention

Non applicable

Sponsors

Nantes University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

: \- clinical suspicion of PAC

Exclusion criteria

: * documented end-of-life * pregnancy * seriously ill patients

Design outcomes

Primary

MeasureTime frameDescription
Frequency of PAC classification modification (definite, probable, possible, excluded) after LUS realizationDay 095% confidence interval of CAP classification modification frequency before and after LUS realization

Secondary

MeasureTime frameDescription
Concordancy of CAP classification diagnosis concordancy ( after LUS) compared to adjudication committee28 days after enrollmentCAP classification (definite, probable, possible, excluded) and kappa coefficient.
Frequency of Antibiotic prescription modification after LUSDay 095% confidence interval of antibiotic prescription intention frequency

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026