Acne Vulgaris, Helicobacter Pylori Infection
Conditions
Keywords
acne vlugaris, prevalence, Helicobacter Pylori
Brief summary
The objective of the study is to investigate prevalence of H.Pylori infection among acne vulgaris patients.
Detailed description
The study included patients with acne vulgaris and healthy control participants. The study recruited both sexes, all grades of acne, adolescents and young adults. All patients were subjected to complete history, general and skin examination Acne vlugaris Patients were classified into mild, moderate and severe according to the classification of American Academy of dermatology for acne vulgaris. Detection of H. pylori infection: Blood and stool samples were taken from each participant and was directly transferred to laboratory for detection of H. Pylori antigen and antibody. An enzyme-linked immune sorbent assay (ELISA) was used for quantitative assessment of IgG antibodies against H.Pylori in human serum. A monoclonal antibodies based enzyme-linked immunosorbent assay was used to detect H.Pylori specific antigen in stool samples.
Interventions
OTHERBlood and stool samples collection
Collection of blood and stool samples from each participants for H.pylori antigen/ antibody detection
Sponsors
Sohag University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
12 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Acne vulgaris patients * Healthy volunteers (control)
Exclusion criteria
* Patients with a history of drug intake that affects H. Pylori such as proton-pump inhibitors, clarithromycin, tetracyclines, amoxicillin or metronidazole within previous two weeks were excluded.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| H.pylori infection | one year | Prevalence of H.pylori infection among acne group and control group |
Countries
Egypt
Outcome results
None listed