Surgery
Conditions
Keywords
intrathecal analgesia, colorectal, enhanced recovery
Brief summary
Multimodal analgesia, sometimes including intrathecal analgesia (IA), is essential in any enhanced recovery pathway (ERP). This study aimed to evaluate the safety, feasibility, and optimal IA regimen in colorectal surgical patients.
Interventions
All intrathecal injections were performed preoperatively using a 22g or 25 g Whitacre or 24g Sprotte spinal needle. The IA regimen, medication(s) and dose(s), was at the discretion of the attending anesthesiologist, and consisted of one of the following regimens: (1) hydromorphone + local anesthetic (IA-L), or (2) hydromorphone only (IA-O). In patients receiving IA, no other interventional locoregional analgesic techniques (such as rectus sheath blocks or transversus abdominis plane blocks) were utilized.
Sponsors
Mayo Clinic
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* All adult colorectal patients from October 2012 through December 2013 in which patients received single-injection IA as part of a multimodal analgesic strategy for ERP. * Undergoing an elective colorectal operation (minimally invasive or open)
Exclusion criteria
* Patients aged \< 18 years * American Society of Anesthesiologists (ASA) 5 and 6 classification * pregnancy * failure to provide research authorization. * emergent operations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Time to return of bowel function | post resection, approximately up to 48 hours | Time to return of bowel function is defined by the presence of flatus and a bowel movement |
Countries
United States
Outcome results
None listed