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The Role of Satiety in the Effect of Portion Size on Intake

The Role of Satiety in the Effect of Portion Size on Intake

Status
Terminated
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03409601
Enrollment
14
Registered
2018-01-24
Start date
2018-04-02
Completion date
2018-12-14
Last updated
2019-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Feeding Behavior

Keywords

Obesity, eating behavior, food, nutrition

Brief summary

The study uses a crossover design in which the portion size of food is varied at each meal. Across four test meals, subjects will be served four different portions of food, and intake will be determined from pre- and post-meal food weights. The first visit will be a screening visit, at which subjects will complete the consent form, have their height and weight measured, and rate the taste of the study food. Test meals will be scheduled once a week for four weeks. At visits 2-5, subjects will eat lunch and rate characteristics of the meal. At visit 6, subjects will complete various questionnaires. The objective of this study is to determine whether any individual characteristics related to satiety influence the effect of portion size on intake.

Interventions

Meal portion size at baseline

Meal portion size 125% of baseline

Meal portion size 150% of baseline

Meal portion size 175% of baseline

Sponsors

Penn State University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Be willing and able to travel to Penn State University Park campus weekly for meals * Be a man or woman 18 - 60 years old * Regularly eat 3 meals/day * Be willing to avoid alcohol the day before and during test days * Have a body mass index between 18.0 and 35.0 kg/m-squared * Be willing to refrain from eating after 10 pm the evening before test sessions

Exclusion criteria

* A smoker * An athlete in training * Pregnant or breastfeeding at the time of screening * Have taken prescription or non-prescription drugs that may affect appetite or food intake within the last 3 months * Dislike or be unable to eat the test foods (because of allergies, intolerance, or dietary restrictions) * Currently dieting to gain or lose weight * Have a health condition that affects appetite * Have participated in a similar study in our lab in the past year

Design outcomes

Primary

MeasureTime frameDescription
Differences in energy intakeWeeks 1, 2, 3, and 4Calculated energy intake (kcal) based on weight and energy density of food consumed
Differences in intake by weightWeeks 1, 2, 3, and 4Weights (grams) of all foods consumed

Secondary

MeasureTime frameDescription
Ratings of hunger and satietyWeeks 1, 2, 3, and 4100-point visual analog scales
Sensory-specific satietyWeeks 1, 2, 3, and 4Change in taste pleasantness of eaten foods compared to uneaten foods
Ratings of meal characteristicsWeeks 1, 2, 3, and 4100-point visual analog scales
Ratings of sensory characteristics of the foodWeeks 1, 2, 3, and 4100-point visual analog scales
Eating rateWeeks 1, 2, 3, and 4Assessed from meal duration and number of bites taken

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026