C2-C4 Compartment Block Versus Block of Costagliola, in TEAC

The Effectiveness of C2-C4 Compartment Block Versus Block of Costagliola, in the Control of Persistent Postoperative Pain in Patients Undergoing Carotid Thromboendarterectomy

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03409068

Acronym

TEAC

Enrollment

100

Registered

2018-01-24

Start date

2018-03-28

Completion date

2019-01-18

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathic Pain, Somatic Pain

Keywords

Carotid thromboendarterectomy, Carotidodynia

Brief summary

C2-C4 compartment block compared to the Costaiola block, in the control of persistent postoperative pain (somatic and neuropathic) in patients undergoing carotid thromboendarterectomy

Detailed description

A comparative analysis will assess the somatic pain (scores ≥4 on the NRS scale) and neurapathic pain (by the Lindblom roller and Von Frei hair tests) between group A (block group of the C2-C4 compartment ) and the control group B (block group according to Costagliola), during the 3 months after surgery.

Interventions

PROCEDUREC2-C4 compartment anesthetic block

C2-C4 compartment anesthetic block is performed by injecting levobupivacaine 0.375% 20 mL between the posterior face of the middle scalenus muscle, the anterior face of the posterior scalene muscle and the lower plane of the sternoscleidomastoid muscle.

PROCEDURECostagliola block

Costagliola block is performed by injected by injecting levobupivacaine 0.375% 20 mL along the anterior and the posterior border of sternocleidomastoid muscle

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* patients undergoing to carotid thromboendarterectomy

Exclusion criteria

* ASA status: 4 * pregnancy * BMI \> 39,99 * neurological impairment * neck anatomical abnormalities * status of sepsis * coagulopathy * neck cancer * neck infections

Design outcomes

Primary

Measure	Time frame	Description
somatic pain	3 mounths after surgery	Somatic pain assessed by Numeric Pain Rating Scale for pain (the 11-point numeric scale ranges from '0' representing no pain to '10' representing the worst pain imaginable

Secondary

Measure	Time frame	Description
Neuropathic pain	3 months	Presence of neuropathic disturbances, assessed with von Frey hair test and Lindblom test
Opiates request	3 mounths after surgery	Request of opiates, assessed in mg of equianalgesic dose of morphine after 3 mouths from surgery
Pregabalin request	3 months	Pregabalin request in mg, 3 months after surgery

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026