Skip to content

Pleural Effusions After Cardiac Surgery

Pleural Effusions Are Associated With Adverse Outcomes After Cardiac Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03409055
Enrollment
11198
Registered
2018-01-24
Start date
2006-01-01
Completion date
2019-12-31
Last updated
2021-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pleura; Effusion

Brief summary

Pleural effusions occur commonly in patients recovering from cardiac surgery, however, the impact on outcomes is not well characterized. The purpose of this study is to characterize the outcomes of cardiac surgery patients with pleural effusions. All patients undergoing cardiac surgery between 2006 and 2019 were included in this observational, cross-sectional analysis using propensity matching.

Detailed description

Pleural effusions are common in patients recovering from cardiac surgery. Symptomatic patients with pleural effusions complain of shortness of breath, cough, chest pain and are more hypoxic and tachypneic. Clinically significant effusions can slow recovery in the hospital and beyond, and are a critical source of hospital readmissions after discharge. It is not well characterized how this impacts hospital outcomes. Further it is unknown if the effusions themselves are associated with impaired outcomes, or if pleural effusions simply arise in more complicated, older patients, thus suggesting the impaired outcomes are the result of coexisting morbidities. To better understand the impact of this complication and to address the question mentioned before, this study was carried out to determine the clinical and economic outcomes of pleural effusions in propensity-matched patients during early recovery from cardiac surgery. To compare patient groups with and without pleural effusion, the following baseline characteristics were used: e.g. age, sex, body-mass-index, priority of surgery, type of surgery, duration of surgery, APACHE II Score of patients on admission in the ICU.

Interventions

None listed

Sponsors

Charite University, Berlin, Germany
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* In-patients of the Charité Universitätsmedizin Berlin * at least 18 years old * female or male sex * cardiosurgical intervention (OPS 5.35 and 5.36) between 01/06 and 12/19 * post-operative monitoring in the intensive care unit

Exclusion criteria

* previous cardiosurgical interventions during the same hospital stay * incomplete documentation.

Design outcomes

Primary

MeasureTime frameDescription
mortalityan average of 30 daysIn-Hospital mortality
hospital stayan average of 30 daysLength of hospital stay

Secondary

MeasureTime frameDescription
renal replacementan average of 30 daysincidence of renal replacement therapy
Need of drainagean average of 30 daysIncidence of drainage in patients with pleural effusions
ICU stayan average of 15 daysLength of Intensive Care Unit (ICU) stay
transfusionsan average of 30 daysnumber of transfusions needed
extubationan average of 15 hourstime to extubation

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026