Healthy
Conditions
Keywords
meal ingestion, meal tolerance, postprandial responses, hedonic sensations, homeostatic sensations
Brief summary
Aim: to determine the effect of gender on the responses to meal ingestion. Participants (10 men and 10 women) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 4 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. Participants will ingest a probe meal up to the level of maximal satiation. The probe meal will be served stepwise (150 Kcal every 5 min). Perception of homeostatic (hunger/satiation, fullness) and hedonic (digestive well-being, mood) sensations will be measured at 5 min intervals 10 min before, during and 20 min after ingestion at 10 min intervals.
Interventions
OTHERprobe meal
The probe meal will be served in 150 Kcal portions (10 g foie, 10 g cheese, 5 g chips, 2 g peanuts, 3 g toast, and 27 mL soft drink) up to the level of maximal satiation.
Sponsors
Hospital Universitari Vall d'Hebron Research Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* non-obese
Exclusion criteria
* history of gastrointestinal symptoms * prior obesity * use of medications * history of anosmia and ageusia * current dieting * alcohol abuse * psychological disorders * eating disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Meal tolerance | 100 min | Amount of meal (Kcal) consumed up to the level of maximal satiation (score 5 on a - 5 to + 5 score hunger/satiation scale). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in digestive well-being induced by the probe meal | 1 day | Change in well-being measured by 10 score scales during and after the probe meal. |
| Change in fullness sensation induced by the probe meal | 1 day | Change in fullness sensation measured by 10 score scales during and after the probe meal. |
| Change in mood induced by the probe meal | 1 day | Change in mood measured by 10 score scales during and after the probe meal. |
| Change in abdominal discomfort induced by the probe meal | 1 day | Change in abdominal discomfort measured by 10 score scales during and after the probe meal. |
| Change in hunger/satiety induced by the probe meal | 1 day | Change in hunger/satiety measured by 10 score scales during and after the probe meal. |
Countries
Spain
Outcome results
None listed