Alzheimer Disease
Conditions
Keywords
Alzheimer Disease, Objective parameters, Scheltens index
Brief summary
The early diagnosis of Alzheimer's disease is essential to enable patients to have access to the available treatments. However, there is a delay between the diagnosis and the onset of symptoms, which can range from 1 year to more than 5 years. In clinical practice, the hippocampal volume, measured by the Scheltens index, is currently used as a marker of the progression of the disease. The purpose of this study is to determine whether the patient's sex, age and ethnicity can influence the delay in the expression of cognitive troubles reported by the family at the first medical consultation, as well as to determine if there is a correlation between the delay reported by the family and the Scheltens index.
Interventions
OTHERMedical file data extraction
Medical file data extraction
Sponsors
Murielle Surquin
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
Alzheimer Disease patients admitted in the 'Memory Clinic' of the CHU Brugmann Hospital between 01-01-2010 and 31-01-2013. Diagnose according to the Dubois criteria
Exclusion criteria
None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Age | Between 01-01-2010 and 31-01-2013 | Age |
| Sex | Between 01-01-2010 and 31-01-2013 | Sex |
| Ethnic origin | Between 01-01-2010 and 31-01-2013 | Ethnic origin |
| Symptoms-diagnose time interval | Between 01-01-2010 and 31-01-2013 | Interval of time between the apparition of the first symptoms, as reported by the family, and the diagnose. |
| Scheltens scale | Between 01-01-2010 and 31-01-2013 | Evaluation of the hippocampal atrophy by means of magnetic resonance imaging. Scale from 0 (normal) to 4. |
Countries
Belgium
Outcome results
None listed