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Sodium Bicarbonate Supplementation in Combat Sports Athletes

The Effect of Sodium Bicarbonate Supplementation on Physical and Specific Performance Capacity in Combat Sports Athletes

Status
Completed
Phases
Phase 2Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03406065
Enrollment
64
Registered
2018-01-23
Start date
2014-10-10
Completion date
2015-04-05
Last updated
2018-01-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sport, Supplementation

Keywords

Sodium bicarbonate, NaHCO3, Combat Sports, Physical capacity, Dummy test

Brief summary

The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on physical and specific performance capacity, as well as concentrations of the selected biochemical blood markers in trained combat sports athletes, in a randomised, double-blind, placebo-controlled trial.

Detailed description

Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive-dose NaHCO3 ingestion on physical capacity and specific performance capacity, and concentrations of the selected biochemical blood markers in trained combat sports athletes, in a randomised, double-blind, placebo-controlled trial.

Interventions

The experimental procedure for each athlete included a 10-day NaHCO3 supplementation in a progressive-dose regimen in order to reduce the likelihood of gastrointestinal side effects (from 25 to 100 mg ∙ kg-1). NaHCO3 was administered in the form of unmarked disk-shaped tablets (Alkala T, SANUM, Poland). The tablets were ingested with at least 250 mL of water and could be either swallowed or dissolved in the mouth. On training days the supplements were taken in the morning, in the evening and 1.5 hours before training session. On rest days the supplements were taken in the morning, in the afternoon and in the evening.

DIETARY_SUPPLEMENTPlacebo treatment

The experimental procedure for each athlete included a 10-day placebo administration. Placebo was ingested with at least 250 mL of water. On training days the supplements were taken in the morning, in the evening and 1.5 hours before training session. On rest days the supplements were taken in the morning, in the afternoon and in the evening.

Sponsors

Poznan University of PhysED
CollaboratorINDIV
Poznan University of Life Sciences
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
17 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* written informed consent from all participants before the study (included aslo informed consents to the participation in the study of athletes under the age of 18 obtained from their parents) * a current medical clearance to practice sports, * training experience: at least 4 years (of combat sport training), * minimum of 4 workout sessions (combat sport) a week,

Exclusion criteria

* current injury, * any health-related contraindication, * declared general feeling of being unwell, * unwilling to follow the study protocol.

Design outcomes

Primary

MeasureTime frameDescription
Changes in specific performance capacity after sodium bicarbonate supplementationBaseline and after 10 daysThe wrestler's special endurance test - projective test with dummy (DT)
Changes in anaerobic capacity after sodium bicarbonate supplementationBaseline and after 10 daysThe Wingate Anaerobic Test (WAnT)

Secondary

MeasureTime frameDescription
Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementationBaseline and after 10 daysHemoglobin (Hb) \[g/dl\] and glucose \[g/dl\] concentration analysis
Changes in blood hematocrit levels after sodium bicarbonate supplementationBaseline and after 10 daysHematocrit (HCT) \[%\] level analysis
Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementationBaseline and after 10 daysLactate \[mmol/L\] and pyruvate \[mmol/L\] concentration analysis
Changes in polyphenols and albumin concentrationBaseline and after 10 daysPolyphenols \[g/L\] and and albumin \[g/L\] concentration analysis
Changes in FRAP concentrationBaseline and after 10 daysFRAP \[µmol/L\] concentration analysis
Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementationBaseline and after 10 daysRed blood cells (RBC) \[mln/mm³\] and white blood cells (WBC) \[mln/mm³\] concentration analysis
Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementationBaseline and after 10 daysCreatine kinase \[U/L\] and lactate dehydrogenase \[U/L\] activity analysis

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026