Pulmonary Hypertension
Conditions
Brief summary
Clinical improvement has been demonstrated after cardiorespiratory rehabilitation in patients with pulmonary hypertension. Rehabilitation is therefore now part of the recommendations for good practice. However, no data is available to elucidate the mechanism of this improvement: an improvement in myocardial reserve or an improvement in peripheral muscular capacity? The main objective of this study is to evaluate the difference in right ventricular contractile reserve before and after cardiorespiratory rehabilitation during stress ultrasound in pulmonary hypertension in 10 patients with pulmonary hypertension.
Interventions
A stress echocardiography will be performed in addition to the traditional patient care
Sponsors
Centre Hospitalier Universitaire de Nice
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Major patients * Proven pulmonary hypertension: PAPm ≥ 25mmHg, known PH * Group 1,3,4 or 5 of the pulmonary hypertension classification * Clinical stability \> 1 month clinically determined by clinician * NYHA II or III class * Signature of informed consent form following appropriate information * Patient affiliated to the Social Security System
Exclusion criteria
* Associated left heart disease * Complex congenital heart disease * Acoustic window which does not allow the echocardiography to be performed correctly * Permanent cardiac arrhythmia * NYHA IV class and NYHA I class * Inability to perform at least a minimal effort on an ergometer * Unstabilized acute coronary syndrome * Compensatory heart failure * Disturbances of ventricular rhythm veins, may not be narrowed. * Prevalence of high-risk embolic intracardiac thrombus * Prevalence of high-risk embolic intracardiac thrombus * Preference of a medium to high abundance peericard-like thinning. * Venous thromboembolic venous thromboembolic disease (\> 3 months) * Left ventricular ejector obstruction (severe and/or symptomatic) * Persons under guardianship, under curatorship, protected by law * Persons deprived of their liberty * Pregnant and parturient women * Major not able or unable to express consent * Minors * Inability to perform cardiac rehabilitation * Modynamic instability * Follow-up impossible for geographical or psychological reasons * Inadequate command of the French language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of the subpulmonary ITS at effort >20% (presence of a right ventricular contractile reserve) defined by the improvement of the ITS or integral subpulmonary time-speed) | 4 months |
Countries
France
Outcome results
None listed