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L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension

Comparative Clinical Study Evaluating the Effect of L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension

Status
UNKNOWN
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03402191
Enrollment
60
Registered
2018-01-18
Start date
2016-07-31
Completion date
2023-12-31
Last updated
2018-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thalassemia

Brief summary

This study compares L-arginine Versus Sildenafil as treatment for pulmonary hypertension in Children with Beta Thalassemia

Detailed description

This study focuses on different lines of treatment for pulmonary hypertension in children with thalassemia as this study discusses the Effect of L-arginine Versus Sildenafil in Children with Beta Thalassemia Associated with Pulmonary Hypertension

Interventions

DRUGL-arginine

l-arginine for thalassemia with pulmonary hypertension

DRUGSildenafil

Sildenafil for thalassemia with pulmonary hypertension

Sponsors

Sherief Abd-Elsalam
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
6 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Children with thalassemia and pulmonary hypertension.

Exclusion criteria

* Rheumatic heart diseases. * Other comorbid disease

Design outcomes

Primary

MeasureTime frameDescription
Number of patients with improvement of pulmonary hypertension6 monthspatients with improvement of pulmonary hypertension

Countries

Egypt

Contacts

Primary ContactSherief Abd-Elsalam, MD
sheriefabdelsalam@yahoo.com00201095159522

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026