The Effect of Anesthesia Type on Pulmonary Function

The Effect of General or Spinal Anesthesia on Pulmonary Function Tests in Geriatric Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03399201

Enrollment

Registered

2018-01-16

Start date

2018-02-16

Completion date

2018-12-02

Last updated

2018-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia, Geriatric Patients

Brief summary

The role of neuraxial anesthesia in preventing respiratory complications is a controversial in elderly patients. The aim of the study was to evaluate the benefits of neuraxial anesthesia on pulmonary function during post-operative term in geriatric patients undergoing to elective non-abdominal surgery.

Detailed description

Sixty elder patients will be randomly assigned to General anesthesia or Neuraxial anesthesia groups. Spirometry, will be performed at pre-operative and post-operative terms. Pulmonary function tests will be evaluated.

Interventions

PROCEDUREGeneral anesthesia

induction with the intravenous anesthetic (Propofol) and maintenance with the inhalational anesthetic (Sevoflurane)

PROCEDURENeuraxial anesthesia

Spinal anesthesia will be applied via the local anesthetic ( Bupivacaine).

DIAGNOSTIC_TESTSpirometer

Pulmonary function will be evaluated via the portable spirometer (MIR Spirodoc, Spirodoc®, Roma, Italy)

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

65 Years to 95 Years

Healthy volunteers

Inclusion criteria

* 65 years of age * Undergoing non-abdominal surgery under anesthesia in supine position

Exclusion criteria

* Pulmonary disease * Hematological disease * Undergoing Abdominal surgery * Non-supine position during surgery * Nicotine Abuse

Design outcomes

Primary

Measure	Time frame	Description
The changes on forced vital capacity	At Preoperative, postoperative 2. hours, postoperative 24. hours	Forced vital capacity will be measured via spirometer
The changes on forced expiratory volume in 1 s	At Preoperative, postoperative 2. hours, postoperative 24. hours	Forced expiratory volume in 1 s will be measured via spirometer
The changes on mid-expiratory flow (MEF 25-75)	At Preoperative, postoperative 2. hours, postoperative 24. hours	mid-expiratory flow (MEF 25-75) will be measured via spirometer
The changes on peak expiratory flow (PEF)	At Preoperative, postoperative 2. hours, postoperative 24. hours	Peak expiratory flow (PEF) will be measured by the spirometer

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026