Cognitive Flexibility Training in Persistent Pain

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03398408

Enrollment

150

Registered

2018-01-12

Start date

2017-12-29

Completion date

2019-08-07

Last updated

2020-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Pain

Brief summary

To determine whether participation in a cognitive training program over a training period of five weeks improves cognitive flexibility in patients with chronic hip, knee, and back pain.

Detailed description

This project is a single-center prospective, randomized study to assess whether cognitive flexibility can be improved through training on a Lumosity®-based training module over the course a five week timeframe in patients with chronic hip, knee, and back pain; and whether changes in cognitive flexibility will correlate with perceived pain scores.

Interventions

BEHAVIORALTraining

The intervention group will be provided with the cognitive training module and participants will be required to complete a targeted 36-minute daily training for 35 days.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Adults age 18 to 70 with chronic hip, knee, or low back pain for \>3 months * Documented moderate to severe chronic pain * English as a primary language * Access to a computer at home and an email account

Exclusion criteria

* Diagnosed Alzheimer's or documented severe cognitive impairment * Lack of email/lack of basic computer skills * Has undergone an interventional pain procedure within one week prior to enrollment * Are scheduled to undergo a pain procedure during the five weeks of complete cognitive training

Design outcomes

Primary

Measure	Time frame	Description
Does cognitive training over five weeks improve cognitive flexibility performance scores in chronic hip, knee, and back pain patients?	Up to 5 months	The primary outcome, i.e. NCPT score, will be assessed before and after five weeks of cognitive training. T-test will be used to compare the change in NCPT score between the training and the control group.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026