ICSI
Conditions
Brief summary
Daily supplement of magnesium after biochemical diagnosis of pregnancy in females pregnant after ICSI and through out 1st trimester
Detailed description
a fall of magnesium levels at 2-3 weeks of gestation. This drop of magnesium concentration is larger following IVF as compared to spontaneous pregnancies. so magnesium supplement start after biochemical diagnosis of pregnancy and throughout the 1st trimester
Interventions
DRUGMagnesium Oxide
After biochemical diagnosis of pregnancy each participant will receive magnesium plus 500 mg tablet once daily till the end of the 1st trimester
DRUGPlacebo Oral Tablet
After biochemical diagnosis of pregnancy each participant will receive placebo tablet once daily till the end of the 1st trimester
Sponsors
Ain Shams University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
25 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
* age 25\_38 years * BMI 25\_30 * females pregnant after ICSI after biochemical diagnosis of pregnancy
Exclusion criteria
* females with poor ovarian reserve and poor responders * abnormality in uterine cavity detected by hysteroscopic evaluation pre ICSI and not treated * hydrosalpinx
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 1st trimesteric abortion | 13 week of gestation | Either spontaneous or missed abortion |
Countries
Egypt
Contacts
Primary ContactRadwa R Ali, MD
Outcome results
None listed