Chronic Kidney Diseases, Renal Insufficiency, Chronic
Conditions
Keywords
taste threshold, salt restriction
Brief summary
The compliance of salt restriction in patients with CKD may be associated with taste sensitivity.
Interventions
OTHERsalt restriction education
Salt intake target：\<5g/d Method：the standard salt restriction education will be lasting for 10-15 minutes by oral explanation at baseline.
Sponsors
Peking University First Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Inclusion criteria
* stage 3-5 CKD patients * clinical stable
Exclusion criteria
* renal replacement therapy * cancer * systemic infection * Alzheimer's disease * acute cardiovascular events, active hepatitis * all other study-obstructive conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ratings of taste sensitivity assessed by the ISO method of investigating sensitivity of taste（ISO 3972:1991） | up to 12 weeks after intervention | Taste sensitivity is measured by five taste solutions（salty、sour、bitter、sweet、umami). Every taste solution contains 8 different concentration. Detection , recognition and difference thresholds will be measured .Their definitions are as bellow. Detection threshold：minimum value of sensory stimulus needed to give rise to a sensation. The sensation need not be identified. Recognition threshold：minimum value of a sensory stimulus permitting identification of the sensation perceived. Difference threshold：value of the smallest perceptible difference in the physical intensity of a stimulus. |
Countries
China
Outcome results
None listed