Skip to content

Hepatitis B Prevalence in the Turkish Population Living in Middle Limburg

Prevalence and Risk Factors of Hepatitis B Viral Infection in the Turkish Population Living in Belgium

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03396458
Acronym
HBVTR
Enrollment
1000
Registered
2018-01-11
Start date
2017-09-01
Completion date
2020-08-31
Last updated
2020-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis B

Keywords

Hepatitis B, Disease prevalence, Screening, Migrant, Turkish, Belgium

Brief summary

This study will assess HBV (HBsAg, anti-HBc and anti-HBs) prevalence in the Turkish population living in Belgium. Additionally, the investigators will determine the risk factors for HBV infection and the uptake of screening, vaccination and antiviral treatment in this hard-to-reach Turkish population.

Detailed description

HBV infection is an important public health problem in the Turkish population, i.e. one of the largest migrant populations in Europe. With the introduction of cost-effective antiviral treatments in the past decade, there is a need to identify HBV infected patients who may benefit from treatment. This study will assess the HBV prevalence in the Turkish population living in Belgium. Additionally, the investigators will determine the risk factors of HBV infection and the uptake of screening, vaccination and antiviral treatment in this hard-to-reach Turkish population. A cross-sectional, epidemiological trial will be conducted in the region Middle Limburg Belgium, where the Turkish adult population (subjects born in Turkey or subjects of which one of the parents is born in Turkey), 18 years of age and older, will be screened for HBsAg, anti-HBs and anti-HBc. Educational meetings concerning viral hepatitis B will be organized and there will be three ways to be screened for HBV: (1) immediately after the educational meetings, (2) at the Outpatient Hepatology Department of Ziekenhuis Oost-Limburg (ZOL) and (3) at home visits. Subsequently, participants will be asked to fill in a questionnaire regarding sociodemographic factors, migration history, risk factors for HBV infection (e.g. sharing toothbrushes, HBV infected family member) and HBV vaccination status. One year after data collection, HBsAg positive patients will be assessed whether they are under follow-up at the general practitioner or hepatologist. The investigators will also gather information regarding the uptake of vaccination in non-immunized subjects. This study will provide information about the HBV prevalence and distribution of the stages of liver disease in the Turkish population in Belgium. By determining the risk factors for HBV infection, subgroups with an increased prevalence of HBV infection can be identified. This study will also give information on how to organize the healthcare system for screening in hard-to-reach migrant groups and to develop care paths.

Interventions

DIAGNOSTIC_TESTHepatitis B serology

A serum specimen will be taken and assessed for hepatitis B serology (HBsAg, anti-HBs and anti-HBc).

OTHERQuestionnaire

Participants will be asked to fill in a questionnaire regarding sociodemographic factors, migration history, risk factors for HBV infection (e.g. sharing toothbrushes, HBV infected family member) and HBV vaccination status.

Sponsors

Hasselt University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Turkish origin, defined as one of the parents born in Turkey * Having a signed informed consent form

Exclusion criteria

/

Design outcomes

Primary

MeasureTime frameDescription
Seroprevalence of current HBV infection in the Turkish population1 daySerum HBsAg

Secondary

MeasureTime frameDescription
Seroprevalence of protective antibodies against HBV infection in the Turkish population1 daySerum anti-HBs
Assess risk factors for past or current HBV infecion in the Turkish population1 dayCombine results from (1) serum anti-HBc with (2) questionnaire regarding sociodemographic factors, migration, risk factors for HBV infection and HBV vaccination status

Countries

Belgium

Contacts

Primary ContactGeert Robaeys, M.D., Ph.D.
geert.robaeys@zol.be+3289326505
Backup ContactÖzgür Koc, M.D.
ozgur.koc@zol.be+3289321519

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026