Case Control Study
Conditions
Brief summary
Does vitamin D is more deficient in women with unexplained infertility than in fertile pregnant women or not?
Detailed description
The study will be done on women with unexplained infertility as a case group and fertile pregnant women as control group to detect if there's a difference in serum level of vitamin D between two groups which will help in the future for curing unexplained infertility women.
Interventions
None listed
Sponsors
Ain Shams Maternity Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 38 Years
Healthy volunteers
No
Inclusion criteria
* women with unexplained infertility. * pregnant fertile women as control group.
Exclusion criteria
* • Endocrinopathies such as (diabetes mellitus, thyroid disorders, parathyroid disorders and hyperprolactinemia), cardiovascular related diseases, severe infection, malignancies and concomitant diseases contribute to Vit D deficiency. * Women with ovulatory factor like PCOS,anovulation and poor ovarian reserve are excluded. * Women with endometriosis are excluded. * Women with autoimmune diseases like antiphospholipid antibodies or lupus erythematosus are excluded. * Documented uterine anomalies, tubal factor, cervical factor and other local causes of infertility. * Male factor of infertility is excluded. * Bone and metabolic disease, liver diseases and kidney related diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vitamin D level | 6 months | Serum vitamin D level in women with unexplained infertility and fertile pregnant women. |
Contacts
Primary ContactSobhy R Mohammed, MBBCH
Backup ContactAhmed M Bahaa eldin, MD
Outcome results
None listed