Breast Cancer Survivors
Conditions
Brief summary
To study the effects of green coffee supplement on adropin, irisin, vaspine, systemic inflammation and oxidative stress in breast cancer survivors.50 breast cancer survivors who their treatment is over and referred to follow breast cancer clinic with will be randomly allocated to receive placebos or 2 capsules green coffe for 12 weeks; both groups will be advised to adherence the investigators' diet and exercise program too. At the first and the end of the intervention, adropin, irisin, vaspine, systemic inflammation and oxidative stress will be assessed and compared between groups.
Interventions
DIETARY_SUPPLEMENTgreen coffee
2 capsuls
OTHERcontrol
2 capsuls
Sponsors
National Nutrition and Food Technology Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Age of 18 to 70 years * Body Mass Index (BMI) between 25-40 treatment is over
Exclusion criteria
* Taking any kind of supplement for weight reduction * pregnancy or lactation * Professional athletes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tumor necrosis factor alpha | 12 weeks | assessed by ELISA |
| Interleukin 6 | 12 weeks | assessed by ELISA |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| body mass index | 12 weeks | The body mass index (BMI) or Quetelet index is a value derived from the mass (weight) and height of an individual. The BMI is defined as the body mass divided by the square of the body height, and is universally expressed in units of kg/m2, resulting from mass in kilograms and height in metres. |
Countries
Iran
Contacts
Primary ContactEhsan Hejazi, PhD
Outcome results
None listed