Aging, Aortic Aneurysm, Abdominal, Arrythmia, Carotid Atherosclerosis, Diabetes, Hypertension, Mass Screening, Peripheral Arterial Disease
Conditions
Keywords
Mass screening, cardiovascular disease, diabetes
Brief summary
This is an intersectional and interdisciplinary screening program in Viborg Municipality, including 67 years old citizens. This observational study will estimate the cost-effectiveness of a combined screening program for the following conditions: Abdominal aortic aneurysm, peripheral arterial disease, carotid plaque, hypertension, arrhythmia, and type-2-diabetes. Furthermore, the incidence of the outlined conditions will be described and so will the result of the intervention initiated (secondary medical prophylaxis, smoking cessation, introduction to nutritionally deficient diet etc.)
Detailed description
Description of the cohort: All Viborg municipality citizen are invited to the combined screening program around there 67th birthday. Participants with positive screening results are offered following up consultations and prophylactic interventions are initiated (secondary medical prophylaxis, smoking cessation, introduction to nutritionally deficient diet etc.) 67 years-old citizens from the surrounding municipalities without the offer of the combined screening are used as a control group (1 case: 5 controls). There are no exclusion criteria. The screening examination includes: Blood pressure in both arms, ankle brachial blood pressure index (ABI), ultrasound for carotid plaque and abdominal aortic aneurysm, HbA1c and pulmonary function test. Furthermore, a questionnaire on lifestyle parameters, BMI, medical history, walking-related pain and self-rated quality of life (EQ-5D). One year after the screening examination, the participants will receive a questionnaire in order to evaluate the effect from a participant perspective. The cost(-effectiveness) of the screening program will be estimated after 5 years based on prevalence of diseases, response rate, data extraction from nationwide registries and existing evidence of disease prevention.
Interventions
None listed
Sponsors
Odense University Hospital
Central Jutland Regional Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
67 Years to 67 Years
Healthy volunteers
Yes
Inclusion criteria
All Viborg municipality citizen are invited to the combined screening program around there 67th birthday.
Exclusion criteria
There are no
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Baseline prevalence of diabetes | Inclusion will take place from sep. 2014 to sep. 2020 | Bedside HbA1c |
| Baseline prevalence of peripheral arterial disease (PAD) in men and women aged 67 years from a population screening study on the Municipal of Viborg. | Inclusion will take place from sep. 2014 to sep. 2020 | Ankel Brachial Index |
| Baseline prevalence of abdominal aortic aneurysm (AAA) | Inclusion will take place from sep. 2014 to sep. 2020 | Ultra sound examination (AP diameter (mm)) |
| Baseline prevalence of carotic plaques | Inclusion will take place from sep. 2014 to sep. 2020 | Ultra sound examination of A. carotis (IMT in mm) |
| Baseline prevalence of hypertension | Inclusion will take place from sep. 2014 to sep. 2020 | BP(mmhg) |
| Baseline prevalence of cardiac arrythmia | Inclusion will take place from sep. 2014 to sep. 2020 | ECG |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The cost(-effectiveness) of the screening program | 5 years after ending inclusion | Socio-economic evaluation (national register data), QALY |
Countries
Denmark
Outcome results
None listed