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Public Health Messages to Address Vaccine Hesitancy

Developing and Evaluating Public Health Messages to Address Vaccine Hesitancy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03395106
Enrollment
883
Registered
2018-01-10
Start date
2018-07-09
Completion date
2018-11-09
Last updated
2019-10-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaccine Hesitancy

Keywords

vaccine, public health

Brief summary

Views on vaccines range from those who are strongly supportive to those who are stridently opposed and will not budge from identity-based core beliefs about vaccines. In between these poles are numerous others who can delay, be reluctant (but still accept), or refuse/accept some vaccines for their children but not others. It is for these vaccine-hesitant parents that constitute the 'middle ground' of this spectrum where the most immediate and productive gains can be made towards enhancing vaccination acceptance and improving uptake. However, navigating this noisy communications environment is difficult, given the array of confusing and conflicting information available from multiple and competing sources. To date, there is no consensus on how best to use communication to respond to vaccine hesitancy. Building on two Canada-wide surveys of parents, the goal of this research is to identify which communication strategies show the greatest impact in reducing parental vaccine hesitancy and improving vaccination intentions. The specific objectives are to: 1. Develop and pre-test four variations of news media stories that vary by source (parent versus physician) and content (intuitive versus deliberative); 2. Examine the impact of vaccine hesitant parents' exposure to vaccine communications that vary in source (parent versus physician) and content (intuitive versus deliberative) on primary (vaccine hesitant attitudes) and secondary (vaccine intentions) outcomes; and 3. Explore which media story variation may be more effective in improving vaccination attitudes and intentions for different parental decision-making styles (deliberative versus intuitive).

Interventions

BEHAVIORALParent source

Having a parent feature prominently in a news story

BEHAVIORALDoctor source

Having a doctor feature prominently in a news story

BEHAVIORALDeliberative content

News story content includes process of weighing the risks/benefits of vaccinating, the importance of vaccines for community protection, and concludes with a recommendation to vaccinate.

BEHAVIORALIntuitive content

News story content focuses on the consequences of not vaccinating (including vaccine preventable diseases) and the decisional regret.

Sponsors

Canadian Immunization Research Network
CollaboratorNETWORK
University of Manitoba
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Outcomes Assessor)

Masking description

Statisticians completing the analysis of the primary outcome will be blinded.

Intervention model description

Factorial design 2x2

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Parents over 18 living in Canada with a YOUNGEST child is less than 24 months.

Exclusion criteria

* Parents who have a YOUNGEST child older than 24 months * A parent who is pregnant, before the first trimester is complete

Design outcomes

Primary

MeasureTime frameDescription
Vaccine HesitancyChange in baseline measured up to 1 day after content deliveryParent Attitudes about Childhood Vaccines (PACV). The PACV is a validated 15 question survey on vaccine hesitancy.

Secondary

MeasureTime frameDescription
Intention to VaccinateChange in baseline measured up to 1 day after content deliveryintention to vaccinate item using a 5 point likert scale ranging from very unlikely to vaccinate to very likely to vaccinate, and see if there is a one-response shift in participant intentions among vaccine hesitant parents.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026