Pleural Effusion, Respiration, Artificial, Ultrasonography
Conditions
Keywords
Pleural effusion, Mechanical Ventilation, Ultrasonography, Drainage
Brief summary
Patients with acute respiratory failure (ARF) who were receiving mechanical ventilator support, had significant pleural effusion (both transudates and exudates) and drainage plan were evaluated. Decision to drain, timing and duration of drainage were made by primary physician according to the intensive care unit (ICU) protocols.The estimated amount of effusion (mL) was calculated as the maximum pleura-lung distance (mm) x 20 and significant effusion is accepted as ≥ 800 mL according to thoracic ultrasonography (USG) performed by the intensivist. The amount of effusion drained, mechanical ventilator parameters, arterial blood gas results and hemodynamic data were recorded before, at the 1st hour and at the end of drainage up to 30 days after drainage.
Interventions
PROCEDUREDrainage of the pleural effusion
Sponsors
Dokuz Eylul University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients on mechanical ventilation due to acute respiratory failure * Estimated effusion \> 800 ml according to USG * Have drainage plan according to ICU protocols decided by primary physician
Exclusion criteria
* Have absolute drainage indication (empyema, hemothorax or chylothorax) * predicted duration of mechanical ventilation less than 72 hours * contraindications to drainage, * underlying disease, which prevents lung expansion (chest deformity, central atelectasis) * malignant effusions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation between estimated and drained effusion volume | 1- Estimated effusion volume just before the drainage (by ultrasonography calculated as described in brief summary) 2- Drained effusion volume just after the drainage is terminated up to 30 days after procedure. | Volume of the effusion estimated and drained was recorded (mL) |
| Change in Lung mechanics | 1- Dynamic Compliance just before the drainage 2- Dynamic Compliance just after the drainage is terminated up to 30 days after procedure | Dynamic Compliance (mL/cmH2O) |
| Change in Oxygenation | 1- PaO2/FiO2 just before the drainage 2- PaO2/FiO2 just after the drainage is terminated up to 30 days after procedure | PaO2/FiO2 (fraction of inspired oxygen) |
Outcome results
None listed