Treatment Resistant Carpal Tunnel in RA Patients
Conditions
Brief summary
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy in Rheumatoid arthritis patients proved by nerve conduction studies and ultrasound parameters, this study aims to evaluate the effect of hydro-dissection using insulin versus hyalase versus saline, ultrasounic guided as an effective treatment
Detailed description
Carpal tunnel syndrome (CTS) is a common peripheral entrapment neuropathy in Rheumatoid arthritis patients proved by nerve conduction studies and ultrasound parameters, this study aims to evaluate the effect of hydro-dissection of median nerve inside CT twice injections with interval 2 weeks using insulin and 10 cc saline versus hyalase and 10 cc saline versus 10 cc saline, ultrasounic guided as an effective treatment of CT
Interventions
DRUGHylase
hydro-dissection injection of median nerve inside carpal tunnel using hyalase and 10 cc saline
DRUGInsulin
hydro-dissection injection of median nerve inside carpal tunnel using 10 IU insulin and 10 cc saline
OTHERsaline
hydro-dissection injection of median nerve inside carpal tunnel using 10 cc saline
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Rheumatoid arthritis in remission
Exclusion criteria
* active Rheumatoid arthritis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain intensity | 6 months | Visual analog scale 0-100 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| nerve conduction | 6 months | sensory velocity |
| ultrasound | 6 months | cross sectional area |
Countries
Egypt
Contacts
Primary ContactManal Hassanien, MD
Backup ContactAbdelraheem Elawamy, MD
Outcome results
None listed