Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients

Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Study About Reorganization and Recovery Mechanism of Brain Neural Network for Chronic Stroke Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03392519

Enrollment

Registered

2018-01-08

Start date

2015-08-18

Completion date

2020-07-17

Last updated

2023-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Stroke

Keywords

Brain connectivity, Magnetic resonance imaging, Brain plasticity, Recovery

Brief summary

In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.

Interventions

OTHERChronic stroke

MRI data acquisition and behavioral test

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* more than 3 months post-stroke * ischemic or hemorrhagic stroke * a person who understands the experiment and has a willingness to participate and signs the agreement

Exclusion criteria

* User of artificial heartbeat * Patients with claustrophobia * Patients with metal implants * Patients who are contraindicated for other common MRI

Design outcomes

Primary

Measure	Time frame	Description
Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score	Through study completion, an average of 1 year	Strength of connection is obtained by calculating a correlation coefficient between time courses of both regions in fMRI data.
Correlation coefficient between the FA value of a tract and the Fugl-Meyer Assessment score	Through study completion, an average of 1 year	FA value is obtained by assessing a diffusion anisotropy of a specific tract in DTI data.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026