Arthritis, Health Related Quality of Life, Osteoarthritis
Conditions
Keywords
Partial Trapeziectomy, Tendon Interposition, Trapeziectomy, Thumb Carpometacarpal Joint
Brief summary
The purpose of this study was to measure the differences in Health Related Quality of Life (HRQOL) and functional measurements between two groups of patients with Carpometacarpal Osteoarthritis of the thumb.
Detailed description
Two patient groups, who have been diagnosed with Carpometacarpal Osteoarthritis of the thumb were compared to measure the Health Related Quality of life (HRQOL) and functional outcomes following two different surgical procedures. The first procedure is currently the most used procedure is North America, Trapeziectomy with Ligament Reconstruction and Tendon Interposition (T+LRTI); this procedure is compared to Partial Trapeziectomy and Tendon Interposition (PT+TI). HRQOL is measured using three questionnaires: one generic, one condition specific and one to measure utility (costs). Patients received their procedures from the respective surgeons and then came in for regular follow up at 1, 3, 6 and 12 months. At these follow up visits the questionnaires and functional measurements (including grip, key pinch and tip pinch strength), were completed
Interventions
PROCEDURET+LRTI
T+LRTI is the most commonly used procedure, it removes the entire trapezium
PROCEDUREPT+TI
The PT+TI is less invasive than the T+LRTI as only part of the trapezium is removed
Sponsors
McMaster University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of advanced stage (Eaton stages II-IV) Carpometacarpal joint (CMCJ) osteoarthritis (OA of the thumb * Willingness to undergo surgery for CMCJ OA; * Over the age of 18; * Able to provide informed consent; and * Ability to read and comprehend English to complete the HRQOL questionnaires
Exclusion criteria
* 1\) Diagnosis of Eaton stage I CMCJ OA of the thumb \[17\]; 2) Under the age of 18; 3) Presence of any concomitant hand pathology (including rheumatoid arthritis, neuropathy and traumatic arthritis); and 4) Previous surgery on the same hand or currently under consideration for other unrelated hand surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Health Related Quality of Life (HRQOL) as measured by the Short Form 36v2 (SF-36) | 1 week pre-operatively plus 1, 3, 6 and 12 month post-operatively | The Short-Form 36v2 \[SF-36\] is a Generic HRQOL questionnaire |
| Change in Health Related Quality of Life (HRQOL) as measured by the Disabilities of the Arm, Shoulder and Hand (DASH) | 1 week pre-operatively plus 1, 3, 6 and 12 month post-operatively | The DASH is a condition specific questionnaire |
| Change in HRQOL as measured by The EuroQol-5D-3L [EQ-5D] | 1 week pre-operatively plus 1, 3, 6 and 12 month post-operatively | The EQ-5D is a questionnaire that allows utility to be calculated |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in functional performance as measured by Grip Strength | 1 week pre-operatively and 3, 6 and 12 month post-operatively | Force applied by the hand, measured by a goniometer in kilograms |
| Change in functional performance as measured by Two-Point Pinch Strength | 1 week pre-operatively and 1, 3, 6 and 12 month post-operatively | Force applied by the tip of the thumb and the tip of the index finger, measured by a goniometer in kilograms |
| Change in functional performance as measured by Key Pinch Strength | 1 week pre-operatively and 3, 6 and 12 month post-operatively | Force applied by the pad of the thumb and lateral surface of the index finger, measured by a goniometer in kilograms |
Outcome results
None listed