Hyperglycemic Response and Steroid Administration After Surgery (DexGlySurgery)

Hyperglycemic Response to Steroid Administration After Noncardiac Surgery in Patients With and Without Diabetes

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03390179

Acronym

DexGlySurg

Enrollment

250

Registered

2018-01-04

Start date

2017-09-04

Completion date

2018-02-28

Last updated

2019-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, Healthy

Keywords

diabetes, anesthesia, surgery, glucose

Brief summary

The hyperglycemic response to surgery and the added effect of low-dose steroids (dexamethasone 4 to 8mg), and whether these differ in diabetics and nondiabetics remain unclear. Therefore, we prospectively evaluate the intraoperative and postoperative serum glucose concentrations in diabetics and nondiabetics that received intravenous steroid administration. This multicentre study include \> 250 patients.Primary endpoiunt was glucose concentration at H6 after surgery. Secondary endpoints were glucose concentration at H12 and at H24 and effect of anesthesia (regional anesthesia)

Interventions

DRUGSteroid Drug

mesure of the glucose concentration

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* elective surgery under anesthesia

Exclusion criteria

* \< 50 kg * emergency * insulin therapy * cardiac surgery * refusal * hyperglycemia\> 2g/L

Design outcomes

Primary

Measure	Time frame
glucose concentration	6-8 hour

Secondary

Measure	Time frame
glucose concentration	12 hour
glucose concentraion	24 hour

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026