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Does Cardiac Rehabilitation Reduce the Risk of Recurrence of Atrial Fibrillation Following the First Catheter Ablation?

Does Cardiac Rehabilitation Reduce the Risk of Recurrence of Atrial Fibrillation Following the First Catheter Ablation?

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03389633
Enrollment
462
Registered
2018-01-03
Start date
2007-01-01
Completion date
2016-07-31
Last updated
2018-01-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Brief summary

Many risk factors contribute to the onset of atrial fibrillation. This study is specifically concerned with the effect of addressing these risk factors by cardiac rehabilitation on the risk of recurrence of atrial fibrillation following catheter ablation. A non-randomized, retrospective study was performed on patients treated with a catheter ablation for atrial fibrillation. The intervention group consisted of patients who chose to participate in the cardiac rehabilitation program. The control group only received standard care. The primary objective was to examine whether cardiac rehabilitation following the first ablation for atrial fibrillation resulted in a reduction of the time to or the risk of recurrence of atrial fibrillation or the need for a second ablation within 1 year after the first ablation. A Kaplan-Meier analysis was used to examine the primary objective. The secondary objectives of this study were to examine whether cardiac rehabilitation following the first ablation for atrial fibrillation had an effect on the evolution of the patients' BMI (a Mann-Whitney U test), the number of recurrences of atrial fibrillation (a Poisson regression) and the proportion of patients who need to continue treatment with antiarrhythmics 3 months following the first ablation (a chi-square test).

Detailed description

The intervention group follows a 3 months rehab program consisting of training, education, coaching and medical follow-up. The control group are patients that chose not to follow this program. This is a retrospective non randomized trial

Interventions

OTHERrehabilitation

Sponsors

prof. dr. Paul Dendale
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* an ablation for AF (Atrial fibrillation)

Exclusion criteria

* a complicated ablation * a prosthetic heart valve * a severe valvulopathy, * hyperthyroidism at the time of the ablation, * pregnancy and breastfeeding, * intensive sport (more than 1 hour a day), * a myocardial infarction or a thromboembolic event within 3 months after the ablation, * a pacemaker * end-stage renal disease.

Design outcomes

Primary

MeasureTime frameDescription
Number of recurrences of atrial fibrillation or need for new ablationfrom 3 months after discharge until 1 yearidem

Secondary

MeasureTime frame
The proportion of patients who needed to continue treatment with antiarrhythmicsmonth 3 until one year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026