Cesarean Delivery Affecting Newborn
Conditions
Keywords
Cesarean, newborn, cerebral and renal oxygenation, anesthesia
Brief summary
Neonatal adaptation to extrauterine life has many physiological changes in neonatal organ systems. These adaptative changes may be affected such as type of delivery and anesthesia management at birth. near infrared spectroscopy (NIRS) is a popular non-invasive method that can be used in newborns thus monitorize tissue oxygenation regularly. In this study we have purposed to compare the effects of general anesthesia versus spinal anesthesia on newborn's cerebral and renal oxygenation in elective cesarean operations
Detailed description
The cases divided into two groups those spinal anesthesia group ( group:1; n:30 ) and general anesthesia group (group:2; n:30). The preoperative and intraoperative mean arterial pressures (MAP), heart rate (HR), arterial oxyhemoglobin saturation (SpO2), intraoperative blood loss values of pregnants and 1st-5th minute APGAR scores, preductal and postductal SpO2, perfusion index, heart rates, body temperature, cerebral and renal regional oxygen saturations of newborns after birth have been recorded.
Interventions
DEVICENear infrared spectroscopy (spinal anesthesia)
effect of spinal anesthesia on regional renal and cerebral oxygen saturation in newborns
DEVICENear infrared spectroscopy (general anesthesia)
effect of general anesthesia on regional renal and cerebral oxygen saturation in newborns
Sponsors
Antalya Training and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* patients who undergo elective cesarean * American Society of Anesthesiologists class 1 to 2 * Ability to consent * Gestational age: from 37 to 41 weeks
Exclusion criteria
* Pulmonary disease * History of allergic reaction to local anaesthetics * Peripheral neuropathy * Neurologic disease * Coagulation disorders * newborns with anomalies * low birth weight newborns * newborns needing neonatal resuscitation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in renal and cerebral regional oxygenation (rSO2) in newborn | 60 minutes after birth | Assessed at third and fifth minutes and then every 5 minutes after birth |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| preductal SpO2 | 60 minutes after birth | changes in preductal SpO2 after birth |
| postductal SpO2 | 60 minutes after birth | changes in postductal SpO2 after birth |
| perfusion index | 60 minutes after birth | changes in perfusion index after birth |
| body temperature | 60 minutes after birth | changes in body temperature after birth |
| apgar scores | 1st and 5th minute after birth | changes in apgar scores after birth |
Outcome results
None listed