Laminaria and Misoprostol Before Operative Hysteroscopy

The Use of Laminaria Versus Laminaria Plus Misoprostol Before Operative Hysteroscopy in Nulliparous Women . A Double Blinded Randomized Trial.

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03388827

Enrollment

100

Registered

2018-01-03

Start date

2017-12-20

Completion date

2019-01-31

Last updated

2018-12-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical Spasm

Brief summary

Laminaria and Misoprostol before Operative Hysteroscopy

Detailed description

The use of laminaria versus laminaria plus misoprostol was compared before operative hysteroscopy in nulliparous women to assess the efficacy of both methods in cervical dilatation.

Interventions

DEVICELaminaria tent

Laminaria tent was inserted for 12 hours before Hysteroscopy

DRUGLaminaria plus Misoprostol

Laminaria plus Misoprostol were inserted for 12 hours before Hysteroscopy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Masking description

double blinded

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

nullipara * need hystroscopic intervention

Exclusion criteria

previous pregnancy cervical lesion contraindication to misoprostol \-

Design outcomes

Primary

Measure	Time frame	Description
Preoperative cervical width	12 hours	cervical width in Hegar dilators number

Secondary

Measure	Time frame	Description
adverse effects	24 hours	adverse effects of the method used or hysteroscopy

Countries

Egypt

Contacts

Primary Contactibrahim A EL sharkwy

ibrahimsharkwy@yahoo.com00966554818576

Backup Contactmohamed L elsayed

drmohamedlotfy@yahoo.com00201222442467

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026