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Conjoined Twins: a Report of Four Cases.

Conjoined Twins: a Report of Four Cases.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03388684
Acronym
CT
Enrollment
4
Registered
2018-01-03
Start date
2000-02-29
Completion date
2017-10-31
Last updated
2024-06-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Conjoined Twin

Brief summary

The present study aims to report our experience in conjoined twin separation surgery in Assuit university and pediatric hospital, Assiut university, Assiut, Egypt over a period of 20 years.

Detailed description

A conjoined twin is a subset of monozygotic twin gestation. It's a rare phenomenon with an incidence of 1 in 50,000 to 1:100,000 births with the higher incidence in Africa and Southwest Asia. Based on the terminology proposed by Spencer and colleagues, conjoined twins are classified according to the most prominent site of conjunction into three major groups; First, twins with a ventral union; \[cephalopagus (head), thoracopagus (Thorax), omphalopagus (Abdomen) and ischiopagus (pelvis)\]. Second; twins with a dorsal union; \[pygopagus (sacrum), rachipagus (spine, back) and craniopagus (cranium)\] and lastly; twins with a lateral union that is referred to as parapagus (side). Depending on the aspect of the embryonic disc, the most common types are thoracopagus (19%). Surgical separation of conjoined twins is extremely challenging taking in consideration the high perioperative risk. The low incidence of such surgeries and anatomical variations in each type of conjoined twins makes each separation surgery a unique experience.

Interventions

PROCEDUREConjoined twin separation surgery

This study included 4 case reports on conjoined twins (CT), 2 male and three female patients; 3 of them were parasitic and one was conjoined. We operated upon 2 parasitic and one conjoined. The 1st case died preoperatively.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Days to 30 Days
Healthy volunteers
No

Inclusion criteria

* conjoined twins * symmetrical or * asymmetrical.

Exclusion criteria

* conjoined twins incompatible with life * conjoined twins with decapitating medical illness.

Design outcomes

Primary

MeasureTime frameDescription
Success of the conjoined twin separation surgeryFor each case was the 1 week survivalThe operative details of the separation surgery were written in details and the separation process was showen in pictures.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026