Atrial Fibrillation
Conditions
Brief summary
The investigators aim to find biomarkers to determine the success of pulmonary vein isolation for the treatment of atrial fibrillation.
Detailed description
The investigators perform an observational study in patients undergoing pulmonary vein ablation to treat atrial fibrillation. Additionally, electrophysiological procedures not related to pulmonary vein isolation are also followed. The aim of the study is finding biomarkers that are able to predict short-term outcome of the procedure.The primary endpoint is defined as reoccurrences of atrial fibrillation within the first three months after pulmonary vein isolation.
Interventions
PROCEDURECatheter Ablation
Sponsors
Universitätsklinikum Hamburg-Eppendorf
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* patients with atrial fibrillation scheduled for pulmonary vein isolation with either radiofrequency of cryoballoon * patients scheduled for an electrophysiological study without ablation * patients with a catheter ablation at the cavotricuspid isthmus for the treatment of right atrial flutter
Exclusion criteria
* patients with concurrent pulmonary vein isolation and ablation of the cavotricuspid isthmus * Acute myocardial infarction, coronary artery bypass graft surgery or open heart surgery within less than 3 months prior to inclusion
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients with short term reoccurrences of atrial fibrillation after ablation. | 3 months | Holter ECGs and ECGs after atrial fibrillation ablation |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in heart rate after pulmonary vein isolation | 3 days. | Heart rates are recorded at admission and release from the hospital. |
Countries
Germany
Outcome results
None listed