Arrhythmias Requiring Therapy, Cardiac Pacing, Artificial, Cohort Studies, Pacemaker, Artificial
Conditions
Keywords
Pacemaker, Gender differences, Survival, Retrospective
Brief summary
Previous publications suggest gender difference in outcome parameters after pacemaker implantation. Aim of this study is to investigate gender differences in patients with pacemaker. Implanted devices, indication for implantation and pacemaker follow up data of patients will be included. Survival data including cause of death will be documented. Prevalent comorbidities and relevant laboratory data will be recorded.
Interventions
OTHERNo intervention, retrospective analysis only.
No intervention, retrospective analysis only.
Sponsors
Medical University of Vienna
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* All patients registered in the pacemaker database of the Department of Cardiology at the Medical University Vienna. Patients get registered when clinical follow up of an implanted Pacemaker is done.
Exclusion criteria
* For survival analysis: No valid match of first name AND surname AND date of birth with patients' insurance data. * For analysis of comorbidities: Not a single documented diagnose was found in our electronic clinic-wide patients' information system.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Survival after pacemaker implantation | 10 years | Null hypothesis: There is no survival difference between women and men after pacemaker Implantation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Implantation rates of single- or dual-chamber Pacemaker in women/men. | Data obtained: April 30th, 2015 | Null hypothesis: Women and men have equal implantation rates of single- and dual-chamber pacemakers. |
| Survival of women/men after single- or dual-chamber pacemaker implantation. | 10 years | Null hypothesis: Survival after single- or dual-chamber pacemaker implantation is equal. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Survival and device/lead-replacement in patients with diabetes. | 10 years | Null hypothesis: There is no difference in survival or device/lead-replacement rates in women/men with diabetes. |
| First implantation age in single- or dual-chamber pacemaker | Data obtained: April 30th, 2015 | Null hypothesis: There is no difference in first implantation age between sexes and single- or dual-chamber pacemakers. |
| Laboratory results | Data obtained: March 2nd, 2016 | Null hypothesis: There is no difference between women and men in troponin T, N-terminal pro-brain natriuretic Peptide, HbA1c and low-density lipoprotein. |
| Pacemaker parameters | Data obtained: April 30th, 2015 | Null hypothesis: There is no difference between women and men in pacing threshold and lead impedance. |
| Time to device- or lead-replacement | 10 years | Null hypothesis: There is no difference between women and men in time to device- or lead-replacement. |
| Prevalence of Comorbidities | Survival analysis: 10 years; data obtained: March 2nd, 2016 | Null hypothesis: There is no difference in survival and first pacemaker implantation when selected comorbidity was found. |
Outcome results
None listed