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Concentrate of Autologous Rich Plasma in Growth Factors in the Treatment of the Thin Endometrium

Efficacy and Safety of the Concentrate of Autologous Rich Plasma in Growth Factors in the Treatment of the Thin Endometrium in Patients Undergoing Transfer of Cryo-preserved Embryos: Clinical Trial II.

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03387501
Acronym
APTE
Enrollment
13
Registered
2018-01-02
Start date
2019-05-27
Completion date
2022-07-26
Last updated
2022-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility, Infertility, Female

Brief summary

This study evaluate the percentage of women with thin endometrium who achieve an endometrial thickness equal to or greater than 7 mm after administration of PRGF (plasma rich in growth factors)

Interventions

Intrauterine administration of PRGF

Sponsors

Sara Rafael Fernandez
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Women who signed informed consent. * Women who understand the Spanish language. * Women under 42 years

Exclusion criteria

* Thrombopenia. * Congenital or acquired uterine malformations that reduce embryo implantation or term gestation. * Ovarian tumors. * Benign uterine tumors require surgical treatment * Local acute inflammatory diseases * Patients with malignant tumors requiring chemotherapy. * Patients with acute or chronic infectious or inflammatory diseases requiring active treatment with drugs that may interfere with implantation and gestation. * Chronic treatment with NSAIDs (Nonsteroidal anti-inflammatory drugs)

Design outcomes

Primary

MeasureTime frameDescription
Percentage of women who achieve an endometrial thickness equal to or greater than 7 mm3 days after administration of PRGFMeasurement of the endometrial thickness by ultrasonography.

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026