Oxycontin
Conditions
Keywords
concentration
Brief summary
Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy testpersons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg
Detailed description
Oxycodone is an opioid frequently given orally as a premedication prior to any kind of surgery. The initial studies are performed on healthy test-persons and is not given in surgery. The investigators want to explore serum concentration over time (5h) and relate this to Visual Analoge Scale (VAS) postoperatively but also to given mg/kg 20 female patients between 30 and 60 years will be included after informed consent. They will have day-surgery. The patients will receive 5 mg oxycodone if weighing less than 60 kg and 10 mg if weighing over 60 kg. Serum samples will be taken 1, 2,3,4, and 5 hours after medication intake and serum concentrations will be analyzed
Interventions
DRUGOxycodone
Serum concentration per hour from 1 to 5 h
Sponsors
Sahlgrenska University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
30 Years to 60 Years
Inclusion criteria
* Females \<100kg, non-opioid tolerant, day surgery and informed consent
Exclusion criteria
* In complying to inclusion criterias
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Oxycodone concentration in the blood after oral premedication | 2 days | Concentration study |
| Oxycodone concentrations and pain after oral premedication | 7 day | Visual analoge Scale |
Countries
Sweden
Outcome results
None listed