Osteo Arthritis Knee
Conditions
Keywords
unicompartmental knee, total knee arthroplasty, osteoarthritis
Brief summary
This study is a prospective, randomized trial to compare patient outcomes of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) for the treatment of medial compartment osteoarthritis.
Interventions
PROCEDUREUnicompartmental knee arthroplasty
Implant to replace the medial compartment of a patient with knee osteoarthritis
PROCEDURETotal knee arthroplasty
Implant to replace the knee joint of a patient with knee osteoarthritis
Sponsors
Rush University Medical Center
Anderson Orthopaedic Research Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* medial compartment osteoarthritis of the knee * knee flexion greater than greater than 90 degrees * flexion contracture of less than 10 degrees * varus deformity \< 20 degrees * grade IV degeneration of the medial compartment
Exclusion criteria
* lateral compartment degenerative changes * previous lateral meniscectomy * anterior cruciate ligament deficiency * body mass index \> 40 * inflammatory arthritis * history of septic arthritis * hemoglobin A1c \> 8.0 * chronic liver disease * stage 3A or greater chronic renal disease * active IV drug abuse * patients requiring thromboembolic prophylaxis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Knee Society Score | 1 year | Functional outcome questionnaire ranging from 0-100, with 100 being best |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Revision | 2 years | complication requiring revision surgery |
Countries
United States
Outcome results
None listed