Inspiratory Muscle Training in Pulmonary Hypertension

The Effects of Inspiratory Muscle Training on Exercise Capacity, Physical Activity and Quality of Life in Pulmonary Hypertension

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03385733

Enrollment

Registered

2017-12-28

Start date

2017-10-10

Completion date

2018-02-15

Last updated

2018-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Hypertension

Keywords

pulmonary hypertension, inspiratory muscle training, functional capacity, physical activity

Brief summary

The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.

Detailed description

Pulmonary hypertension (PH) is a condition which is seen with hemodynamic differences, pulmonary vascular resistance and right heart failure. Patients with pulmonary hypertension have, dyspnea, physical inactivity, reduced condition and respiratory muscle dysfunction. Aerobic exercise programs in patients with pulmonary hypertension are reported to result in improved exercise capacity and endurance of the patients, improvement in WHO functional class and quality of life, increased peak workload and increased peripheral muscle function. In recent years, few studies have investigated the efficacy of inspiratory muscle training in patients with PH.The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.

Interventions

OTHERinspiratory muscle training

The treatment group received IMT. Patients were trained using an inspiratory threshold-loading device

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Intervention model description

Patients will randomize into two groups as Group A: inspiratory muscle training, and Group B (control group)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Diagnosis of Pulmonary Hypertension, * NYHA functional class I-IV * MIP pressure \<80 cm h2O

Exclusion criteria

* COPD * Conditions which can limit the assessments * Insufficient cooperation

Design outcomes

Primary

Measure	Time frame	Description
mouth pressures	10 minutes	MIP and MEP

Secondary

Measure	Time frame	Description
Activity monitoring (Sense wear® Armband)	3 days	Metabolic holter
6 minute walking test	15 minutes	functional capacity
International Physical Activity Questionnaire-Short Form	10 minutes	Physical activity
Minnesota Living with Heart Failure Questionnaire	15 minutes	quality of life

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026