Endotracheal Tube
Conditions
Keywords
Endotracheal tube, Intracuff pressure, Minimal occlusive volume technique, Spirometer, Endotracheal sealing
Brief summary
The endotracheal intracuff pressure is to be maintained at a low level to prevent trachea and nerve damages, and yet be high enough to secure air sealing. The objective of the study is to compare minimal occlusive volume technique (MOVT) and expired volume/inspired volume ratio (VE/VI ratio) from a spirometer method of endotracheal tube (ETT) cuff inflation with respect to the cuff pressure required to seal the airway during a laparoscopic surgery under general anesthesia. A study design is a randomized crossover trial in 35 patients. The primary outcome is the intracuff pressure of an endotracheal tube. The study consists of two cuff sealing methods separated by a period of 10 minutes.
Interventions
PROCEDUREMOVT
ETT cuff will be inflated till the disappearance of audible air leak on auscultation, while abdominal carbon dioxide (CO2) inflation is maintained with peak inspiratory pressure of 25 cm H2O during volume controlled ventilation. The patient will be in the Trendelenburg position.
PROCEDUREVE/VI ratio of Spirometer
ETT cuff will be inflated till the VE/VI ratio meets the initial VE/VI ratio, while abdominal CO2 inflation is maintained with peak inspiratory pressure of 25 cm H2O during volume controlled ventilation. The patient will be in the Trendelenburg position.
Sponsors
DongGuk University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
The randomization table of a treatment sequence will be managed by the third person who will not involve in this study.
Intervention model description
Two methods of cuff sealing will be applied in a random sequence to each patient.
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists physical status I, II * Body mass index \< 30 kg/m2 * Elective laparoscopic gynecologic surgery under general anesthesia in the Trendelenburg position
Exclusion criteria
* History of airway-related or pulmonary diseases/abnormalities * When difficult intubation is anticipated * History of general anesthesia within the past 3 months * Pregnancy * History of smoking
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intracuff Pressure | From the start of cuff inflation to the airway sealing, an average of 2 minutes | The intracuff pressure of endotracheal tube when cuff sealing is achieved. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intracuff air volume | From the start of cuff inflation to the airway sealing, an average of 2 minutes | The intracuff air volume of endotracheal tube when cuff sealing is achieved. |
Countries
South Korea
Outcome results
None listed