Stent Placement and the Risk of New-onset AF in Patients With AMI

The Impacts of Different Stent Types in Acute Myocardial Infarction on the Risk of Atrial Fibrillation

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03382990

Enrollment

40000

Registered

2017-12-26

Start date

2018-01-01

Completion date

2019-12-31

Last updated

2017-12-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction, Atrial Fibrillation New Onset

Keywords

Atrial fibrillation, Acute myocardial infarction, Drug-eluting stent

Brief summary

The benefit of a drug-eluting stent (DES) in patients with acute myocardial infarction (AMI) is controversial. This study will aim to observe the effect of a DES on the risk of new-onset AF in patients with AMI.

Detailed description

Acute myocardial infarction (AMI) is the leading cause of mortality in the world. Early invasive strategy with percutaneous coronary intervention (PCI) has been demonstrated to be the most effective strategy to treat AMI. Although drug-eluting stent (DES) has not shown benefits to reduce mortality rate among AMI patients compared with bare-metal stent (BMS), the use of DES in real-world is increasing because of reduced restenosis rates. AMI patients are at higher risk to develop atrial fibrillation (AF) than general population. However, whether early PCI with DES implantation is related to a reduced risk of AF still remains unclear. The purpose of this study is to investigate the association of DES implantation and the risk of AF among patients with AMI treated by early PCI.

Interventions

DEVICEDES or BMS

DES or BMS placement during the procedure of PCI in patients with AMI is depend on the operator's decision.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients were enrolled by primary diagnostic coding as acute myocardial infarction and treatment coding as receiving PCI between 2007 and 2013 in Taiwan National Health Insurance Research Database (NHIRD)

Exclusion criteria

1. Less than 20-years-old; Unknown sex and age 2. Not residents in Taiwan 3. Died during AMI admission 4. Previous history of AF 5. Receiving coronary artery bypass grafting (CABG), ventricular assist device (VAD), extracorporeal membrane oxygenation (ECMO), and heart transplantation during observational and/or database period 6. No stent implantation during PCI 7. Unknown stent types

Design outcomes

Primary

Measure	Time frame	Description
new-onset atrial fibrillation	one year	new record or diagnostic claims of atrial fibrillation after hospital discharge from acute myocardial infarction

Contacts

Primary ContactChao-Feng Lin, MD

thcpci@gmail.com+886-2-2543-3535

Backup ContactLi-Nien Chien, PhD

lnchien@tmu.edu.tw+886-2-6638-2736

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026