Colorectal Cancer
Conditions
Brief summary
In colorectal surgery about 30% of postoperative mortality is attributed to anastomotic leak, whit an incidence range between 1.8% and 15.9%. Preventing the anastomotic leak can therefore bring benefits to the patient and the health system. To date we have technologically advanced suturizers and the correct realization (well-vascularized margins, not in tension, etc.) remains crucial to prevent anastomotic dehiscence. Experimental results demonstrate that modified cyanacrylate is a suitable potential reinforcement on intestinal anastomoses (manual or linear intra-corporeal). Applied after mechanical anastomosis, it polymerizes in a short time, closing the spaces of the suture line between one point and the other, expressing an adhesive, hemostatic and sealing action on the tissues, also creating an effective antiseptic barrier towards of the most common infectious or pathogenic agents.
Interventions
DEVICEcolectomy
colectomy resection
Sponsors
National Cancer Institute, Naples
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Informed consent * patients undergoing to oncologic colorectal surgery with colorectal anastomosis
Exclusion criteria
* refuse informed consent * patients undergoing to oncologic colorectal surgery without colorectal anastomosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fistula incidence | From day of surgery up to 30 postoperative days |
Secondary
| Measure | Time frame |
|---|---|
| anastomitic bleeding | From day of surgery up to 30 postoperative days |
| infection | From day of surgery up to 30 postoperative days |
Countries
Italy
Outcome results
None listed