Dysarthria, Dysphagia, Dysphonia, Dystonia, Primary
Conditions
Brief summary
To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement disorders department for idiopathic oromandibular dystonia and matched, healthy control subjects. Voice and speech disorders had to be assessed with the phonetic analysis, perceptive analysis and motor examination modules of the Batterie d'Evaluation Clinique de la Dysarthrie (Clinical Evaluation of Dysarthria), the Grade, Rough, Breathy, Asthenic, Strained scale, and a computer recording. Activities of daily living had to be assessed with the Oromandibular Dystonia Questionnaire, the Voice Handicap Index and the Deglutition Handicap Index.
Interventions
None listed
Sponsors
University Hospital, Lille
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
8 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Both groups: Man or woman Age \> 18 years French social security French speaking: fluent * Oromandibular dystonia group: Idiopathic oromandibular dystonia (focal or associated to other dystonic symptoms) * Healthy controls group: Same age +/- 2 years than a patient from the oromandibular dystonia group Normal clinical examination
Exclusion criteria
* Both groups: Any pathology making the orthophonic evaluation difficult Property protection regime Deprivation of liberty -Oromandibular dystonia group: Abnormal neurological examination, except dystonic features * Healthy controls group: History of brain lesion Abnormal neurological examination Swallowing difficulties
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| French scale Batterie d'Evaluation Clinique de la Dysarthrie (Clinical Evaluation of Dysarthria) phonetic analysis. | 10 minutes at baseline | To describe the clinical characteristics of dysarthria in idiopathic oromandibular dystonia. Composite score (min=best=0; max=worst=151) including three subscales: phonetic production (min=worst=0; max=best=33); simple words (min=worst=0; max=best=88); complex words (min=wost=0; max=best=30). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| French software Logiciel d'Evaluation Vocale Assistée (Computer-Assisted Voice Assessment): maximum phonation time | 1 minute at baseline | To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. Maximum phonation time was measured in seconds. |
| French software Logiciel d'Evaluation Vocale Assistée (Computer-Assisted Voice Assessment): number of pauses. | 1 minute at baseline | To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. The number of pauses was counted. |
| French software Logiciel d'Evaluation Vocale Assistée (Computer-Assisted Voice Assessment): total lecture time. | 1 minute at baseline | To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. Total lecture time was measured in seconds. |
| French software Logiciel d'Evaluation Vocale Assistée (Computer-Assisted Voice Assessment): pauses duration | 1 minute at baseline | To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. Pauses duration was measured in seconds. |
| French software Logiciel d'Evaluation Vocale Assistée (Computer-Assisted Voice Assessment): fundamental frequency | 1 minute at baseline | To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. Fundamental frequency was measured in Hz |
| French software Logiciel d'Evaluation Vocale Assistée (Computer-Assisted Voice Assessment): repetitions. | 2 minutes at baseline | To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. Repetitions were measured in seconds. |
| French software Logiciel d'Evaluation Vocale Assistée (Computer-Assisted Voice Assessment): mean vocal intensity | 1 minute at baseline | To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. Mean vocal intensity was measured in dB |
| French software Logiciel d'Evaluation Vocale Assistée (Computer-Assisted Voice Assessment): frequency variations | 1 minute at baseline | To describe the clinical characteristics of voice impairment in idiopathic oromandibular dystonia. Frequency variations were measured in Hz. |
| Tohara swallowing test | 5 minutes at baseline | To describe the clinical characteristics of swallowing difficulties in idiopathic oromandibular dystonia. Min=best=0; max=worst=4 |
| Deglutition Handicap Index | 10 minutes at baseline | To describe impairment of daily living activities in idiopathic oromandibular dystonia. Qualitative: 30 questions (possible answers: never; almost never; sometimes; often; always) |
| Oromandibular dystonia questionnaire | 10 minutes at baseline | To describe impairment of daily living activities in idiopathic oromandibular dystonia. Qualitative: 25 questions (possible answers: never; almost never; sometimes; often; always) |
| Grade Rough Breathy Asthenic Strained scale | 5 minutes at baseline | To describe dysphonia: from 0 (normal) to 3 (severe) |
| French scale Batterie d'Evaluation Clinique de la Dysarthrie (Clinical Evaluation of Dysarthria) phonetics characteristics | 5 minutes at baseline | Phonetic characteristics of voice: nine items, each quoted from A (normal) to E (strongly abnormal). |
| French scale Batterie d'Evaluation Clinique de la Dysarthrie (Clinical Evaluation of Dysarthria) perceptive analysis. | 5 minutes at baseline | To describe the clinical characteristics of dysarthria in idiopathic oromandibular dystonia. Perceptive score (min=best=0; max=worst=20) |
| Voice handicap index | 10 minutes at baseline | To describe impairment of daily living activities in idiopathic oromandibular (min=best=0; max=worst=120) |
Countries
France
Outcome results
None listed