Cerebral Hemorrhage, Cerebral Infarction, Stroke, Subarachnoid Hemorrhage, Transient Ischemic Attack
Conditions
Brief summary
Stroke is the first most common cause of death in China and one of the major causes of functional disability in the adult population.The burden of stoke is significantly increased in China in recent years. In order to investigate the prognosis of stroke, with diagnostic and treatment information of traditional Chinese medicine (TCM), and assess the effectiveness and safety of TCM for stroke in southern China, the investigators will conduct this multicenter prospective registry study in southern China. This study will recruit 10,000 consecutive eligible patients with acute stroke from more than 50 hospitals. 24 months follow-up will be carried out on-site in hospitals and by telephone to track endpoint (including all-cause mortality, composite cerebrovascular and cardiovascular events at one and two year follow up, and neurological and functional assessments).
Interventions
OTHERobservational only-no intervention
Observational only and no predesigned interventions in this study.
Sponsors
Yefeng Cai
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. ≥18 years. 2. Patients within 14 days of onset of acute stroke (including acute cerebral infarction, transient ischemic attack, acute cerebral hemorrhage, acute subarachnoid hemorrhage). 3. The patient and/or guardian agree to participate in this study.
Exclusion criteria
1. Patients with silent cerebrovascular disease. 2. Patients with non-cerebrovascular disease events.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All-cause mortality | 12 months follow-up | — |
| Composite cerebrovascular and cardiovascular events | 12 months follow-up | Including stroke recurrence events,acute myocardial infarction and cardiac death |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Modified Rankin Scale(mRS) | 3 months follow-up | Range:Grade 0 to Grade 6, higher grade represent a worse outcome |
| All-cause mortality | 24 months follow-up | — |
| Mini-Mental State Examination(MMSE) | 3 months follow-up | Range:0 to 30 points, higher points represent a better outcome |
| Barthel Index(BI) | 3 months follow-up | Range:0 to 100 points, higher points represent a better outcome |
| Composite cerebrovascular and cardiovascular events | 24 months follow-up | Including stroke recurrence events,acute myocardial infarction and cardiac death |
Countries
China
Contacts
Primary ContactYefeng Cai, M.D.,PhD
Backup ContactXinfeng Guo, PhD
Outcome results
None listed