Prevalence of Strokes Secondary to a Reversible Cerebral Vasoconstriction Attributable to Cannabis Consumption in Young Subjects (≤ 45 Years) Hospitalized for an Ischaemic Stroke

Status

Active, not recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03379857

Acronym

CANNASTROKE

Enrollment

300

Registered

2017-12-20

Start date

2018-01-11

Completion date

2025-01-11

Last updated

2024-02-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cannabis Use, Stroke

Brief summary

Incidence of strokes has increased these last 20 years in young population. This rise could be linked to alcohol, tobacco or drug use like cannabis. Cannabis has previously been descripted as a potential factor of reversible vasoconstriction. The main objective is to show that an exhaustive assessment of a stroke facing a young person frequently lead to a diagnostic of reversible vasoconstriction due to cannabis use. Evaluation will focus on prevalence of strokes secondary to a reversible vasoconstriction attributable to cannabis in young subjects. There's a real public healthcare interest in terms of primary and secondary prevention to evaluate the role of cannabis as a risk factor of stroke in young population.

Interventions

OTHERDrug urinal test

Non Applicable

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Intervention model description

Cannabis User

Eligibility

Sex/Gender

ALL

Age

18 Years to 45 Years

Healthy volunteers

Inclusion criteria

* Subject between 18 and 45 years old * Stroke confirmed by medical imaging * Written informed consent (subject, nearby or emergency procedure) * Subject affiliate to a local healthcare insurance office * For female of childbearing potential, an adequate contraceptive measur

Exclusion criteria

* Subject with psychiatric disorder, unable to understand the study or cooperate * Subject under guardianship or forfeiture of liberty * Pregnant or breastfeeding woman * Subject in period of exclusion due to another study or still in follow-up of an interventional study

Design outcomes

Primary

Measure	Time frame	Description
Evaluation Cannabis use	12 months	—
Reversible vasoconstriction on medical imaging of intracranial arteries at different moment	12 months.	medical imaging of intracranial arteries will show new stenoses (topography, number, evolution), and new ischemic or cerebral haemorrhagic lesions

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026