Novel Equation for Estimating Resting Energy Expenditure

Novel Equation for Estimating Resting Energy(REE) Expenditure in Chronic Kidney Disease(CKD) 3-5 Stages Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03377413

Enrollment

300

Registered

2017-12-19

Start date

2017-12-14

Completion date

2020-02-01

Last updated

2020-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease, Resting Energy Expenditure

Brief summary

The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations are not applicable to CKD patients,so we aim to develop and validate a equation for estimating resting energy expenditure in CKD patients.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* CKD 3-5 stages * Age:18-80 years old

Exclusion criteria

* Dialysis and kidney transplantation; * Acute complications to hospitalization * 1 month prior to the study; * Acute or chronic infections, cancer and other wasting diseases in the past year; * Thyroid dysfunction; * Acute onset of podagra; Musculoskeletal diseases; * Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD); * History of hormonal drugs use; * During pregnancy or lactation

Design outcomes

Primary

Measure	Time frame	Description
Novel equation development	September 1, 2017 to June 1, 2018	Developed equation for estimating REE in CKD 3-5 stages patients
Novel equation validation	June 1, 2018 to March 1, 2019	Validate the noval equation with REE obtained by indirect calorimetry (IC).

Countries

China

Outcome results