Epiretinal Proliferation in Eyes With Full Thickness Macular Hole

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03376776

Enrollment

390

Registered

2017-12-18

Start date

2013-03-31

Completion date

2017-12-31

Last updated

2017-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Disease

Keywords

idiopathic macular hole

Brief summary

We evaluated preoperative and postoperative optical coherence tomograpghic images in eyes with full thickness macular hole (FTMH) whether the epiretinal proliferation (EP) was detected and detection of EP was correlated to the visual improvement.

Detailed description

Interventions

PROCEDUREVitrectomy

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 90 Years

Healthy volunteers

Inclusion criteria

* Eyes with macular hole

Exclusion criteria

* Eyes with retinal detachment, retinal vascular disease, glaucoma, proliferative diabetic retinopathy

Design outcomes

Primary

Measure	Time frame
Recovery of foveal microstructure	6 months

Secondary

Measure	Time frame
Visual improvement	6 months

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026