Pain, Withdrawal
Conditions
Keywords
rocuronium, propofol, pain, withdrawal, venous diameter
Brief summary
During general anesthesia, intravenous (IV) medications can disrupt the patient's comfort by causing a pain sensation or a withdrawal response in the heart. Propofol and rocuronium are among the most common causes of this condition. In recent years, the use of ultrasonography (USG) in anesthesia has become widespread with the rapid advancement of technology. The use of the patient's head is a non invasive method. This study is aimed to evaluate whether the size of the venous diameter assessed by ultrasonography in our study is an effect on pain and withdrawal response after drug injections.
Detailed description
The study was conducted in patients who underwent surgical procedures under general anesthesia by obtaining consent from the Adnan Menderes University Medical Faculty Ethics Board and written consent from the patients and then being admitted to the ASA I-II age group 18-70 years of age. Patients with peripheric vascular disease, vasculitis, rheumatologic disease, non-cooperative, under the age of 18 and over 70, ASA III and above, allergic to general anesthetic agents and refusing to participate in the study were excluded from the study.
Interventions
DIAGNOSTIC_TESTPain Score
Four poin scala 0=No Pain 1. mild 2. intermediate 3. severe
DIAGNOSTIC_TESTWithdrawal movement score
Withdrawal movements 1. no movement response 2. movement limited to the wrist 3. movement limited to the elbow/shoulder, 4. generalized movement response.
DIAGNOSTIC_TESThemodynamic response
Hemodynamic data were recorded in the patients taken in the operation room. (T0). Hemodynamic values (T1) measured 1 minute after administration of intravenous propofol were recorded. Hemodynamic values (T2) measured 1 minute after administration of intravenous rocuronium were recorded. Hemodynamic values (T3) measured 1 minute after administration of endotracheal intubation were recorded.
Sponsors
Aydin Adnan Menderes University
Study design
Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
17 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
18- 70 years of ASA (American society of anesthesiology) physical status I- II who were to undergo various elective operations
Exclusion criteria
Rheumatologic disease Peripheric vascular disease Vasculitis Patients with chronic pain syndrome, Patients with neurologic deficits, Patients with thrombophlebitis, Patients with difficult venous access, Patients with allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The injection pain due to propofol | 6 month | Pain will be recorded and graded using a 4-point scale (none, mild, moderate, or severe). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The withdrawal movement due to rocuronium | 6 month | Withdrawal movements are scored as follows: (a) no movement response, (b) movement limited to the wrist, (c)movement limited to the elbow/shoulder, or (d) generalized movement response. |
Countries
Turkey (Türkiye)
Outcome results
None listed