Post-Operative Myocardial Incident & Atrial Fibrillation

Longitudinal Study of Patients Undergoing Cardiac Surgery or Implantation of a Percutaneous Valve Prosthesis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03376165

Acronym

POMI-AF

Enrollment

1500

Registered

2017-12-18

Start date

2018-01-30

Completion date

2028-01-01

Last updated

2026-05-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease, Valve Heart Disease

Keywords

prognosis, translational research

Brief summary

To explore predictors of major cardio-vascular events after cardiac surgery and trans-catheter valve implantation with a specific interest in studying mechanisms linking pre-operative leukocyte, fat and myocardial phenotypes with post-intervention outcomes.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients scheduled for cardiac surgery (coronary artery bypass graft surgery and/or valvular surgery) or transcatheter valve implantation

Exclusion criteria

* pregnant woman * urgent surgery or intervention * not able to consent to the protocol

Design outcomes

Primary

Measure	Time frame	Description
major cardio-vascular events after cardiac intervention (surgery or transcatheter valve implantation)	from the day of intervention to 10 years	cardiovascular death, hospitalisation for heart failure, stroke, myocardial infarction, re-intervention

Secondary

Measure	Time frame	Description
peri-operative myocardial injury	3 days following intervention	Area Under the Curve of blood troponin release during the 3 days following cardiac intervention
post-operative myocardial infarction (type 5 myocardial infarction)	10 days following intervention	myocardial infarction during the peri-operative time
post-operative atrial fibrillation	10 days following intervention	atrial fibrillation onset during post-op hospitalisation
major cardio-vascular events after cardiac intervention (surgery or transcatheter valve implantation)	from the day of intervention to 1 year	cardiovascular death, hospitalisation for heart failure, stroke, myocardial infarction, re-intervention

Countries

France

Contacts

CONTACTDavid Montaigne, Prof.

david.montaigne@chru-lille.fr320445230

PRINCIPAL_INVESTIGATORDavid Montaigne, Prof.

University Hospital, Lille

Outcome results