Cystic Fibrosis
Conditions
Keywords
Cystic Fibrosis, Inspiratory Muscle Training, Chest Physiotherapy, Balance, Postural Stability, Pulmonary Function Test, 6-Minute Walk Test
Brief summary
It is extensively reported in the literature that patients with chronic obstructive lung disease may have impairments in balance and postural control which further increase the disease burden. Mechanisms related to these impairments include, but are not limited to increased work of breathing, diaphragm weakness, peripheral muscle weakness and systemic inflammation. Since the similar symptoms are reported for the children with cystic fibrosis, it is hypothesized that balance and postural control may also be compromised in these patients. Inspiratory muscle training (IMT) is shown to improve diaphragm strength and pulmonary function. Considering the relation between diaphragm which is one of the core muscles, and balance, IMT may also have an impact on postural control and balance alongside the standard clinical parameters such as respiratory muscle strength, pulmonary function and functional capacity in these patients. Thus, the aim of this study was to investigate the effects of inspiratory muscle training and conventional chest physiotherapy on postural stability, balance, pulmonary function and functional capacity in children with cystic fibrosis.
Interventions
Programme will include diaphragmatic breathing exercise, thoracic expansion exercises, incentive spirometer exercise (Triflo), oscillatory PEP (Flutter), postural drainage and coughing tecniques.
OTHERInspiratory muscle training
Threshold IMT device will be used for the training. Training intensity will set at 30% of the maximum inspiratory pressure.
Sponsors
Bezmialem Vakif University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
8 Years to 18 Years
Healthy volunteers
No
Inclusion criteria
* Cystic fibrosis diagnosis * Stable clinical condition (no exacerbation in last 4 weeks)
Exclusion criteria
* Documented diagnosis of vestibular, neurological or orthopedic disorders which may affect balance and mobility * Subjects previously involved in exercise training or physiotherapy programs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline distance covered in six-minute walk test at 8 weeks | Eight weeks |
| Change from baseline postural stability test score in Biodex Balance System SD at 8 weeks | Eight weeks |
| Change from baseline limits of stability test score in Biodex Balance System SD at 8 weeks | Eight weeks |
| Change from baseline sensory integriation and balance test score in Biodex Balance System SD at 8 weeks | Eight weeks |
| Change from baseline Forced Vital Capacity (FVC) at 8 weeks | Eight weeks |
| Change from baseline Forced Expiratory Volume in 1 second (FEV1) at 8 weeks | Eight weeks |
| Change from baseline Peak Expiratory Flow (PEF) at 8 weeks | Eight weeks |
| Change from baseline maximum inspiratory pressure at 8 weeks | Eight weeks |
| Change from baseline maximum expiratory pressure at 8 weeks | Eight weeks |
Secondary
| Measure | Time frame |
|---|---|
| Change from baseline m. quadriceps strength at 8 weeks | Eight weeks |
Countries
Turkey (Türkiye)
Outcome results
None listed