Hepatocellular Carcinoma, Radiofrequency Ablation
Conditions
Brief summary
The aim of this study is to evaluate clinical outcome of RFA for small single nodular HCC using no touch technique with separable clustered electrode (Octopus) in a prospective multicenter manner Participating center: Seoul national university hospital, Asan medical center, Samsung medical center, Kunkuk university hospital, St. mary's Seoul hospital
Interventions
PROCEDURERFA
thermal ablation using radiofrequency for HCC
Sponsors
Starmed
Seoul National University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* Child-Pugh class A liver function * 1 - 2.5 cm sized Single nodular HCC * without history of previous HCC treatment or with evidence of no recurrence at least 2 years after previous HCC treatment
Exclusion criteria
* more than 2 HCC * tumor size larger than 2.5 cm * Child-Pugh class B or C liver function * invisible tumor even after real-time fusion US guidance * accompanied by vascular invasion or distant metastasis * presence of coagulopathy defined as platelet count \< 50,000/mm3 and/or PT-INR \> 50%
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 1 year local tumor progression | 1 year after procedure | cumulative incidence of local tumor progression after RFA |
Countries
South Korea
Outcome results
None listed