Involutional Ptosis
Conditions
Brief summary
Involutional ptosis is a known eyelid pathology in which the eyelid margin obscures part of the visual axis (MRD1).Patients usually complains of visual field disturbance, deterioration in quality of life and a poor cosmetic appearance. In clinical practice, two main surgical approaches are performed to the repair of involutional ptosis: 1. anterior approach - skin incision and levator muscle insertion advancement. 2. posterior approach - eyelid reversion and tarsectomy Both approaches has its pro's and con's, but to this date, no solid evidence exists to prove which of these techniques is superior in manner of anatomical and functional results. in this prospective study, patients with involutional ptosis will be randomized to each of surgical approaches groups, parameters concerning surgical and post surgical periods will be evaluated.
Detailed description
Involutional ptosis is a known eyelid pathology in which the eyelid margin obscures part of the visual axis (MRD1).Patients usually complains of visual field disturbance, deterioration in quality of life and a poor cosmetic appearance. In clinical practice, two main surgical approaches are performed to the repair of involutional ptosis: 1. anterior approach - skin incision and levator muscle insertion advancement. 2. posterior approach - eyelid reversion and tarsectomy Both approaches has its pro's and con's, but to this date, no solid evidence exists to prove which of these techniques is superior in manner of anatomical and functional results. in this prospective study, patients with involutional ptosis will be randomized to each of surgical approaches groups, parameters concerning surgical and post surgical periods will be evaluated.
Interventions
PROCEDUREBlepharoptosis repair
levator advancement or mullerectomy
Sponsors
Meir Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Involutional ptosis * No previous eyelid surgery
Exclusion criteria
* Previous eyelid surgery or trauma * Congenital ptosis * Previous glaucoma filtrartion surgery * Unwillingness for six months followup
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| MRD1 | 6 months | Distance in millimeters between corneal light reflex and upper eyelid margin |
| surgery duration | 3 hours | Time from first incision to last suture (in minutes) |
| Levator function | 6 months | change (in millimeters) in upper eyelid position from downgaze to maximal upgaze |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Need for additional eyelid surgery | 6 months | Any need for oculoplastic additional surgical interventions (Descriptive) |
| Eyelid or ocular secondary disease | 6 months | Descriptive |
Contacts
Primary ContactArie Nemet, Prof. (MD)
Backup ContactTal Sharon, Dr.(MD)
Outcome results
None listed