Colorectal Polyp
Conditions
Brief summary
In this randomized control trial the investigators aim to compare the bleeding complication between cold snaring and hot snaring polypectomy with a large sample size.
Detailed description
The investigators will enroll subjects who receive screening or surveillance colonoscopy with small colorectal polyp, 4 to10 mm in size, from multiple centers in Taiwan. Subjects who are less than 40 years old and has contraindication will be excluded from this study. All the candidates for enrollment will sign the inform consent at the outpatient clinic. Once the candidate has the target lesion, polyp sized 4 to 10 mm, at colonoscopy will be randomized into either cold snaring or hot snaring polypectomy group. In the group with cold snaring, polypectomy will be done without electrocautery. In the hot snaring group, the polypectomy will be performed with electrocautery. The bowel preparation and colonoscopy insertion are the same in both groups as conventional colonoscopy method. The colonoscopy will be performed by experienced endoscopies who performed more than 100 polypectomies per year.
Interventions
Polypectomy during colonoscopy is considered effective to reduce the incidence and mortality of colorectal cancer
Sponsors
Study design
Eligibility
Inclusion criteria
* Candidate has the target lesion, polyp sized 4 to 10 mm, at colonoscopy
Exclusion criteria
* Subjects who are less than 40 years old and has contraindication will be excluded from this study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Delayed bleeding rate | 2 weeks | Anal bleeding with spontaneously stop; drop of Hb more than 2 gm/dl in comparison with baseline; transfusion needed; hemostasis by : colonoscopy, angiography, surgery |
Countries
Taiwan