Circulatory; Change, Liver Dysfunction
Conditions
Brief summary
Hepatocellular insufficiency is a dreaded complication after hepatectomy, since, if it is persistent, it leads to the death of the patient in the absence of liver transplantation. The preoperative evaluation aims in particular to estimate the risk of postoperative hepatocellular insufficiency so as to minimize or contraindicate high-risk patients. It has been shown that the flow of the portal vein is correlated with liver function, especially in the living donor and after portal embolization. More recently, the study of flow rates in the portal vein and the hepatic artery after transplantation has shown a correlation with the recovery of graft function. The hypothesis is that portal and arterial flow after hepatectomy can predict postoperative hepatocellular function.
Detailed description
Measurements of flow rates in the portal vein and the hepatic artery by different transit times are available thanks to the Medistim VeriQTM system that the investigators already use routinely in the context of liver transplantation when performing hepatectomies.
Interventions
PROCEDURELiver debit measure
Mesure of liver debit during hepatectomy
Sponsors
University Hospital, Tours
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient 18 years or more * Patient undergoing laparotomy for liver resection
Exclusion criteria
* Patient under tutorship or curatorship * Pregnant or lactating woman * Difficulties in understanding French * Patient operated by laparoscopy * Patient having objected to the processing of his data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Liver vessel debit | Baseline | Mesure of liver debit during hepatectomy |
Countries
France
Outcome results
None listed